The co-relation between gastrointestinal stromal tumors and renal cell carcinoma: is the largest retrospective analysis ever performed enough evidence?

The subject of gastrointestinal stromal tumors (GIST) has been widely researched over the past few decades since its discovery in 1983 (1-3), due to the fact that they stand for the most common sarcoma-type tumor in the gastrointestinal tract. Lately, however, it has been noticed that some smaller studies, or case reports, with approximately 1–3 patients, have been taking the first steps towards the understanding of the relationship between the GIST and the renal cells carcinoma (RCC) (4-8).